Research Articles
Strategies for Process Mass Intensity (PMI) Reduction in Drug Workup and Isolation: A Sustainable Approach for Modern Drug Development
This article provides a comprehensive guide for researchers and drug development professionals on reducing Process Mass Intensity (PMI) during the workup and isolation stages of pharmaceutical development.
Reducing Process Mass Intensity (PMI) in Pharma: A Strategic Guide to Continuous Manufacturing
This article provides a comprehensive guide for researchers, scientists, and drug development professionals on leveraging continuous manufacturing to significantly reduce Process Mass Intensity (PMI).
Reducing Process Mass Intensity in Biocatalysis: Sustainable Strategies for Pharmaceutical Manufacturing
This article provides researchers, scientists, and drug development professionals with a comprehensive framework for reducing Process Mass Intensity (PMI) in biocatalytic processes.
How to Use the ACS GCI PMI Calculator: A Step-by-Step Guide for Sustainable Drug Development
This guide provides researchers, scientists, and drug development professionals with a comprehensive understanding of how to effectively use the ACS Green Chemistry Institute (GCI) Pharmaceutical Roundtable's Process Mass Intensity (PMI)...
PAT for Real-Time Process Monitoring and Improvement (PMI) in Biopharma: A Guide to Implementation and Innovation
This article provides a comprehensive overview of Process Analytical Technology (PAT) for real-time Process Monitoring and Improvement (PMI) in biopharmaceutical development and manufacturing.
How to Calculate Process Mass Intensity (PMI) for Drug Substance: A Guide for Sustainable Pharma Development
This article provides a comprehensive guide for researchers, scientists, and drug development professionals on calculating and applying Process Mass Intensity (PMI) for drug substances.
PMI in API Manufacturing: The Essential Guide to Metrics, Methods, and Sustainable Optimization
This article provides a comprehensive guide to Process Mass Intensity (PMI) for researchers, scientists, and drug development professionals.
Process Mass Intensity vs Manufacturing Mass Intensity: A Strategic Guide for Sustainable Drug Development
This article provides a comprehensive analysis of mass intensity metrics for researchers, scientists, and drug development professionals.
Greenness Assessment in HPTLC: A Comprehensive Comparison of NP-HPTLC vs. RP-HPTLC for Sustainable Pharmaceutical Analysis
This article provides a systematic comparison of the greenness profiles of Normal-Phase (NP) and Reversed-Phase (RP) High-Performance Thin-Layer Chromatography (HPTLC) for pharmaceutical analysis.
Analytical Eco-Scale vs. AGREE: A Strategic Guide to Green Method Assessment for Pharmaceutical Scientists
This article provides a comprehensive comparison of two pivotal green analytical chemistry (GAC) tools—the Analytical Eco-Scale and the AGREE metric—tailored for researchers and professionals in drug development.